The sloping park (suggesting shifting ground?) great calamity (suggesting earthquakes) through l'Hesperie (the Lands of the West, the New World; more specifically, possibly America) and Lombardy (a region of northern Italy).The fire in the ship (suggesting naval warfare?) plague (an affliction or the spread of disease) and captivity (suggesting a military occupation through war?); Mercury in Sagittarius, Saturn fading (an astrological position occurring next on November 25, 2015; then on November 23, 2016; and again on December 7, 2044)"

Could 2015 or 2016 be the years that earthquakes will occur in the United States and Italy?

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Trouble could occur in California, or New York City (where three fault lines rest under Manhattan Island). An even larger disaster could occur in the region known as the New Madrid fault line (as referenced in the quatrain below).

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All the old roads will be improved, and one will travel down them to the modern Memphis, the grand Mercury of Hercules fleur-de-lys, causing the land, sea, and country to tremble, the old roads will be improved (this places us in at least the 20th century), one will travel down them (by automobile?) to modern Memphis (possibly suggesting Memphis, Tennessee)The grand Mercury (Mercury was the Roman god of travel, commerce, and thievery, who served as a messenger to the other gods and was a common figure in alchemy) of Hercules (the mythological immortal son of Zeus who was a hero of extraordinary strength).Fleur-de-lys ("fleur-de-lys" is associated with the Bourbons -- a French royal family, perhaps Nostradamus is making an esoteric allusion to himself in this line)

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Causing the land (the geographic region of the central-southern United States), sea (possibly suggesting the Gulf of Mexico and the Atlantic Ocean), and country (an allusion to the United States of America) to tremble (suggesting an earthquake will occur, perhaps in the region comprising the New Madrid fault line, which will be so powerful in the magnitude of its destruction that it will affect the central and southern states along the Mississippi River, as well as the southeastern coastal areas of the United States).

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California has always, remains a very unstable area of America.